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(2012) performed a meta-analysis including 779 patients from three studies, which, however, the authors saw as seriously compromised by details of trial designs 19

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A 2015 permeation study confirmed near-zero transdermal delivery through untreated skin (Li et al., 2015)

The endogenous-acetylcholine-induced VEGF expression in neurons and astrocytes [302], the VEGF signaling system is in the rescuing effect of acetylcholine on NMDA-induced long-lasting hippocampal cell damage [303]
