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doi:10.1016/j.hepres.2005.12.005

PEI forms a positively charged complex with DNA, which binds to anionic cell surface residues and enters the cell via endocytosis 16,17 , keeping the dispersed state in the solution 18

The neurotoxicity of 5- S -cysteinyl catecholamines may be due to their further oxidation to benzothiazine species, such as DHBT-1 (dihydrobenzothiazine-1-(2-aminoethyl)-3,4-dihydro-5-hydroxy-2 H -1,4-benzothiazine-3-carboxylic acid) (Shen et al., 1996, Shen et al., 1997, Vauzour et al., 2008)

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