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To cope with the elevated oxidative stress they generate, cancer cells enhance their antioxidant capacity, largely through sustained activation of the transcription factor NRF2 often driven by mutations in its negative regulator KEAP1

It's the same as if an anti-biotic was unsuitable for a patient, we don't just prescribe it." This is largely due to the strict code of conduct that physicians must operate by

doi: 10.1111/jfpe.13792 288 JanTNegiRHilalAKaurSKourDKhanSSet al

doi: 10.1152/ajpcell.1998.275.6.C1640
