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A recent screening-based study has identified several promising SARM1 inhibitors, including non-competitive inhibitors such as berberine chloride and zinc chloride 233 , suggesting the presence of an allosteric binding pocket that can be targeted for therapeutic development

Both of these problems mean that cobalamin deficiency is mainly caused by its insufficient intake (a common complication of a vegetarian or vegan diet) or intestinal absorption disorders of vitamin B12, which occur in the course of diseases of various origins (Table 1) [41]

Reconstitution technique also plays a role

10, 26 Oct