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[DOI] [PubMed] [Google Scholar] 6.Florini J.R., Ewton D.Z., Coolican S.A

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A deficiency in vitamin B12 can lead to a range of symptoms that can affect both physical and mental health

A course of injections is highly recommended for B12, for example a course of 4 every few weeks to begin with, moving forward it can be repeated once every few months to ensure regular levels are maintained.

Methotrexate modulates tight junctions through NF-B, MEK, and JNK pathways
