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10.1016/j.tips.2023.07.007 17 TenopoulouM.KurzT.DouliasP

Avoid harsh scrubs that may worsen inflammation

Support Bile Flow and Gut Elimination 63,64 Incorporate foods, bitter herbs, or supplementation to stimulate bile production and flow

Future strategies should incorporate personalized microbiome profiling, enabling tailored interventions that target individual microbial deficiencies, optimize immune modulation, and maximize therapeutic efficacy (Porcari et al., 2023)

Recently, we developed a NASH C57BL/6 J mouse model using a P-HFD supplemented with intraperitoneal injections of LPS to simulate gut dysbiosis and endotoxemia