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37 It should be noted that this study was not designed to differentiate between GSH in brain tissue versus CSF

639 Since then, the effect of HODEs in cell proliferation has been recognized and extensively studied

Ferroptosis can therefore be induced by depriving cells of the sulfur-containing GSH precursor, cysteine, via inhibition of the system x c cystine/glutamate antiporter (e.g., using small molecules of the erastin family), or by direct inhibition of GPX4 itself (Forcina & Dixon, 2019)

doi: 10.1080/19396368.2019.1573274

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