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Optimal grids for AMYR:Cagri complexes and CTR: Cagri ( N = 1) were imaged by conventional cryo-TEM on a Thermo Fisher Scientific Titan Krios microscope operated at an accelerating voltage of 300 kV with a 50 m C2 aperture and a 100 m objective aperture at an indicated magnification of 105kx in nanoprobe EFTEM mode, yielding a calibrated pixel sampling of 0.85 .pix -1
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doi: 10.1093/ageing/6.2.123
A 10 mg vial is ideal for the titration phase when weekly doses are small (2-4 mg), because the vial gets used within its optimal potency window
