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In addition, pathways related to hormone stimulus, oxidative stress and endoplasmic reticulum were also enriched (Fig

Among these, monocyte chemoattractant protein 1 (MCP-1) (29), also known as CC chemokine ligand 2, is classified within the CC subfamily of chemokines

Lipid hydroperoxides, generated primarily through the activity of lipoxygenases (LOXs), are key mediators of cellular dysfunction and death ( 2.1.3 Antioxidant system 2.1.3.1 System Xc-/GSH/GPX4 axis The cystine/glutamate antiporter (System Xc-), glutathione (GSH), and glutathione peroxidase 4 (GPX4) form a critical antioxidant axis that plays a central role in regulating ferroptosis

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