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Atpenin A5 is of limited in vivo compatibility, and following its proof-of-concept as broad antiviral agents, more work is necessary to render it biocompatible or find other inhibitors of the same target

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Contrastingly, PD is characterized by the death of dopaminergic (DA) neurons in the substantia nigra pars compacta (SNpc), which, in turn, causes a range of motor symptoms such as resting tremors and muscle rigidity [7]

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Patients often present with fatigue, glossitis, and neurologic symptoms

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