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Regarding corticosterone levels, which directly indicate stress in murine models, a decrease was noted shortly after DSIP exposure

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In contrast, bGH mice, with high GH/IGF-1 levels show decreased VO(2) and increased RQ [30,32,33]

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Methionine is a precursor for the polyamines, spermidine and spermine

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Although, it is important to note that the overall outcome of both animal and human studies seems to be mixed

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