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CPT1a is necessary to transport long-chain fatty acids into the mitochondrial matrix for oxidation, and it is possible that CD8 + T cells instead use short-chain fatty acids, which do not require CPT1a transport to support memory formation
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doi: 10.1210/jc.2013-2218 100 RashidGKhanNAElsoriDYounessRAHassanHSiwanDet al
A total number of 2635 raw movie stacks made of 50 frames each were collected with SerialEM 87 from a single individual session with a GLACIOS 200 kV FEG Cryo-TEM (ThermoFisher Scientific) using a K2 Summit detector (Gatan Inc., USA) at 36000 magnification and pixel size of 1.145 /pixel without pre-exposure and using a defocus of 2.6 to 1.8 m and 50 e - / 2 total dose per stack (1 e - / 2 per frame)
Dose: Every 4 hours until symptoms start to improve
