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The global DNA methylation in the livers of HFD-fed mice was increased, with significant gene-specific hypermethylation of CYP2R1, CYP27A1, CYP27B1, and VDR, and hypomethylation of CYP24A1

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Butyrate modifies intestinal barrier function in IPEC-J2 cells through a selective upregulation of tight junction proteins and activation of the Akt signaling pathway

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These oxylipins are central for signaling during the R phase, working in parallel with GSH for balancing the redox state of the cell