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[Google Scholar] Ravichandran M
Formulation Design and Optimization 3.2.1

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doi: 10.3390/genes11040384 110 SoltaniALebrunSCarpentierGZuninoGChantepieSMazaAet al

The development of an APAP-induced DILI mouse model based on the mechanism by which N-acetyl-p-benzoquinone imine (NAPQI), a reactive metabolite of APAP, induces hepatotoxicity by depleting GSH, led to the discovery of the antidote N-acetylcysteine (NAC), which has been used clinically for over four decades [91]
