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PLoS One 2010

Visible midsection changes by weeks 6-8

Conclusion The present study pointed to the protective effect of PA against APAP-induced hepatotoxicity in mice through ameliorating the functional, biochemical and morphological changes of APAP-induced hepatotoxicity

This cascade establishes a self-perpetuating vicious cycle, wherein systemic inflammation exacerbates gut barrier dysfunction and dysbiosis, which then further fuels the inflammatory response