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From here, they may influence organellar homeostasis on the redox triangle: for instance, the inhibition of peroxisomal catalase, concomitant with increasing ROS, results in mitochondrial redox imbalance 33

There is also the question of what happens when GLP-1 therapy is eventually stopped: weight tends to return, suggesting that the underlying biology of obesity has not been fundamentally altered

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Additionally, due to synergistic side effects of AFM1 + OTA, the accumulation of lipid droplets and liver steatosis were observed in co-treated groups (314)

Mitoma, H., Hadjivassiliou, M