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Description
Pyruvate kinase deficiency varies significantly in severity, from a mild, compensated condition requiring little intervention to a severe disease requiring transfusions

Saiki A., Watanabe F., Murano T., Miyashita Y., Shirai K
This results in the release of stored iron to further increase reactive intracellular iron levels (47)
This reduction in enzyme activity can lead to a compromised ability to catalyze the conversion of O 2 - into H 2 O 2 and O 2
[DOI] [PubMed] [Google Scholar] 344.Wang W, Li Y, Meng X
