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Under oxidative stress, P62 protein can regulate the protein stability of Nrf2 and the transcriptional activity of downstream AREs by directly interacting with KEAP1 [132]
Aristoforin Aristoforin, a hypericin derivative, inhibits the activities of SIRT1 and SIRT2

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This finding directly links ferroptosis to the pathogenesis of OM

To test GRX-dependent oxidation of reduced roGFP2, the reaction was started by adding 50 M GSSG