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Some individuals do fine at standard doses immediately

While this treatment can brighten the skin, they do not permanently alter your natural skin tone

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doi: 10.1038/s41385-020-0264-z 73 KovarikJJBileckAHagnGMeier-MenchesSMFreyTKaempfAet al

Patients with active infections, certain autoimmune conditions, active malignancy, or pregnancy are typically not candidates and these are screened at consultation