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Description

Position-effect variegation (PEV) is a marker of gene silencing via heterochromatin spreading in Drosophila and it is caused from loss of epigenetic modifications, such as histone methylation and acetylation ( hsp70 gene, which in Drosophila is induced by various physical, physiological and chemical stressors

Reverse-phase purification brings the molecule to the 99% release specification, followed by lyophilization into 10 mg vials

2018 Jan;147:141-152

A comprehensive 2025 review in Molecules compiled evidence that the AEDG peptide has been studied for its influence on expression of key antioxidant genes, including SOD2 (superoxide dismutase 2), CAT (catalase), and HMOX1 (heme oxygenase-1) (8)