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Based on the mean cluster size and intra-cluster correlation coefficient, we adjusted the results from trials with the unit of analysis errors (Higgins et al., 2021)

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Dormancy Period: Days

This is particularly important when valproate use is considered for a condition not usually associated with permanent injury or death such as prophylaxis of migraine headache [seeContraindications (4)]

(3) By affecting iron metabolism, it also leads to increased reactive oxygen species which are directly damaging to mitochondria and cause them to release inflammatory compounds