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doi:10.1016/j.toxicon.2017.10.012

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Reprod Biol Endocrinol 7(1):114 Aitken RJ, Gibb Z, Baker MA, Drevet J, Gharagozloo P (2016) Causes and consequences of oxidative stress in spermatozoa

However, this origin-based indicator is not completely trustworthy, as there are cases where melena can develop from gastrointestinal bleeding sources, depending on characteristics such as bleeding rate and intestinal transit time