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Since the ferroptosis was proposed, researchers have revealed the mechanisms of its formation and continue to explore effective inhibitors of ferroptosis in disease

Here, we review the homeostatic and immunoregulatory functions of HO-1, whose induction differentially affect the course of various pathologies

Juhairiyah F, de Lange ECM (2021) Understanding drug delivery to the brain using liposome-based strategies: studies that provide mechanistic insights are essential

Once inside the cell, the intracellular metal reductase STEAP3 reduces Fe3+ back to Fe2 +, which is then released into the cytosolic labile iron pool by the divalent metal transporter 1 [49]

Being a folate antagonist, MTX acts directly upstream of both nucleic acid synthesis and methionine recycling and therefore has the potential to influence methyltransferase activity and alter the epigenome