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& Ghoul M., 2001
IFN activates the JAKs/STAT pathway, increasing the expression of CXCR3 and its ligands CXCL9, CXCL10, and CXCL11, responsible for CD8 + T cell recruitment and apoptosis in melanocytes
Blood Cancer J 14(1):69, 2024
Additional tirzepatide safety concerns include risk of acute gallbladder disease (presenting as right upper quadrant pain, fever, or jaundice), acute kidney injury from dehydration (especially if severe gastrointestinal symptoms occur), and hypersensitivity reactions
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