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David JA, Rifkin WJ, Rabbani PS, Ceradini DJ

Nisar S, Bhat AA, Masoodi T, Hashem S, Akhtar S, Ali TA, et al

In Caenorhabditis elegans, supplementation of individual amino acids, with the exception of phenylalanine and aspartate, extended lifespan ( Drosophila , restriction of the essential amino acids methionine, threonine, histidine, lysine, or BCAAs extends lifespan (Richardson et al., 2021)

Adenovirus infection increases ASNS protein expression and knocking down ASNS levels decreases adenovirus replication (unpublished observation)

Yet, they're still tired, still brain-foggy, and coming in wondering, "Is it something else?" But when we do labs and put them on injections, they can notice the change almost immediately