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The most common side effect is hyperpigmentation and occurs following activation of pigment-producing cells called melanocytes
Sullivan, R.B
For example, insulin/insulin-like growth factor (IGF) signaling (IIS), which affects aging in many model organisms, integrates nutritional cues, and regulates fat storage in many animals (Fontana et al., 2010b)
Oncotarget 7 , 5614756152 (2016)
Talenezhad, M
