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MDA malonaldehyde

Erastin triggers ferroptosis in colorectal cancer cells by activating the PERK-NRF2-HO-1 signaling pathway, thereby exerting potent anti-tumor effects ( 3 Ferroptosis and NAFLD 3.1 Ferroptosis and inflammation Globally, the prevalence of NAFLD continues to rise, encompassing a spectrum of conditions from simple steatosis to NASH, fibrosis, and cirrhosis (45)

Rendn-Ramirez A, Cerbn-Solrzano J, Maldonado-Vega M, Quintanar-Escorza MA, Caldern-Salinas JV

10.1038/nrm1261 Nat

The most common therapy for WD involves the use of copper chelators, such as D-penicillamine and trientine, which were developed by John Walsh in the 1950s