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For example, exposure to PM2.5 has been demonstrated to result in the accumulation of labile iron, an increase in ROS and lipid peroxidation, and the induction of ferroptosis in human nasal epithelial cells
PMID 15731109
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Squitti et al., 2021) The fact that A promotes oxidative stress and accelerates the development of A further demonstrates the relationship between oxidative stress and A (Cheignon et al., 2018) The evidence favoring oxidative stresss central role in AD is convincing
