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284 MAT2A Methylthioadenosine phosphorylase (MTAP)-deficient tumors account for ~15% of solid tumors, including ~15% of NSCLC, 28% of esophageal cancer, 26% of bladder cancer, and 10% of esophagogastric cancer

Die Aussagen bezglich Senkung des Triglyceridspiegels sind ebenfalls nicht eindeutig: In den Metaanalysen von Reiner et al

In the same study, the human colon carcinoma cell line HCT116 was revealed to be less sensitive to the bleomycin treatment, in line with the very low expression of CT2 and with the metabolism based on glycolysis rather than on FAO (Table 1)

Mol Psychiatry 26:51405149

Or And if so, how does one balance or even evaluate the balance between the two apparently contradictory effects