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doi: 10.1007/s10534-010-9329-x

Preclinical studies indicate that senescent cell burden is low in young rodents and increases with chronological age in several tissues (33, 34)

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Further research into novel synthetic strategies, such as the development of sulfinate ester intermediates or DAG (diacetone-d-glucofuranose) methodologies, could provide more efficient and versatile routes for producing SFN and its analogues