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Therefore, similar to the transport of GAA from the kidneys to the liver for creatine synthesis, the GAA produced in certain neural cells must be transported into GAMT expressing cells in order for brain creatine synthesis

However, numerous studies employing cellular, molecular, and animal models have revealed a plethora of interconnected cellular and immunological mechanisms underlying asthma pathogenesis [46]

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The dermis (the thick middle layer of skin) is composed of a complex network called the extracellular matrix, or ECM

Patients who have a deteriorating response to L-dopa, experience fluctuations in response to L-dopa, or have a limited clinical response to L-dopa secondary to an inability to tolerate higher doses are appropriate candidates