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PD-1 inhibition in cancer patients has been linked to the gut microbiota, including Faecalibacterium, Bifidobacterium, and Akkermansia, according to several studies (Wu et al., 2009), direct DNA damage (Tsoi et al., 2017)
In the case of cystic fibrosis, a common treatment, nebulized n-acetylcysteine (NAC), helps loosen the mucus that forms in the lungs

doi: 10.1016/j.cotox.2019.10.003 71 LeemansMCouderqSDemeneixBFiniJ-B

Timing is another important aspect of any study design

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