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Neutrophils, when properly activated, convert arachidonic acid into leukotrienes via the 5-lipoxygenase (5-LOX) pathway, and into prostaglandins and thromboxane A via the cyclooxygenase-2 (COX-2) pathway 5
Products from unregulated sources may be contaminated or incorrectly dosed
In HCC, hypoxic tumor-derived exosomal miR-1290 promotes the polarization of M2 macrophages, triggers apoptosis in CD8+ T cells, and enhances EMT in HCC cells
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While symptoms often resolve with treatment or drainage, in some cases, inflammation from the infection can contribute to chronic tinnitus
