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The first signs of B12 deficiency include persistent fatigue, weakness, lightheadedness, pale skin, tingling or numbness in the hands and feet, difficulty concentrating, and mood changes like irritability or mild depression

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The long-term safety of Astaxanthin supplements in children, pregnant women, and nursing mothers is unknown

Cel Mol Biol 25, 164169

GPX4 Activity Affecting Lipid Peroxidation Leads to Ferroptosis GPX4 is an antioxidant enzyme that neutralizes lipid peroxides and protects membrane fluidity by using glutathione, as a cofactor of GPX4, to protect cells and membranes against peroxidation