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Even though a promising candidate for lifespan extension and SASP repression, multiple side effects including metabolic dysregulation, impaired wound healing, and hyperlipidemia have been reported (85)
NOX is activated by CS to produce ROS in a variety of cell types, including lung epithelial cells [112,113], tracheal and arterial smooth muscle cells [114,115,116], vascular endothelial cells [109,117,118,119], cancer cells [120,121], as well as macrophages and neutrophils [122]

Within the multi-factorial pathological landscape of DKD, ferroptosis is a critical biological link connecting metabolic disorders, oxidative stress, and tissue fibrosis (Li et al., 2023
10.1016/j.clinthera.2014.07.017 32 DalbethN.ChoiH
Tap into the regenerative power of peptides, antioxidants, and coenzymes and feel what its like to turn back the clock from the inside out
