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Description
36 Ferric ions are then released from the transferrin complex by endosomal acidification and reduced to ferrous ions (Fe 2+ ) by six-transmembrane epithelial antigen of prostate 3 (STEAP3), Tf will separate from its receptor TfR1 and re-enter the bloodstream to capture ferric ions

The normal range is 0.5% to 2%

This reduction consists of two steps

Poewe, W.|Barone, P.|Hauser, R.|Mizuno, Y.|Rascol, O.|Busse, M.|Debieuvre, C.|Fraessdorf, M.|Schapira, A

ARID1A deficiency is associated with impaired cystine uptake and ROS induction (39, 40)
