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During aging, mitochondrial function progressively deteriorates, leading to a decline in mitochondrial metabolic flux and consequently exacerbating the deficiency of -KG [119]

This combination affects the menstrual rate of women with PCOS positively, irrespective of their metabolic phenotype and with a higher dose of myo-inositol more evident and insulin-independent effect is seen (de Cicco et al

Infiltration of thyroid tissue with lymphocytes, mainly T helper 1 (Th1) cells, can directly alter thyroid gland function through the mediation of interleukin-1 (IL-1), tumor necrosis factor (TNF) and interferon gamma (IFN-) [14]

it is not recommended for use in children and pregnant women (caffeine content 18 mg in 1 serving)

Bone marrow fat content in 70 adolescent girls with anorexia nervosa: Magnetic resonance imaging and magnetic resonance spectroscopy assessment
