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However, an analysis of the peripheral blood of patients with COPD showed that oral administration of NAC (dose of 400 mg, 3 times a day, for 6 months) increased a proportion of the Treg in the CD4 + T cells and decreased the Th17/Treg ratio, whereas the regulation of the Th17/Treg balance was mediated via the hypoxia-inducible factor (HIF)-1 pathway [125]
Important flavonoids and their role as a therapeutic agent

these findings are modeldependent and primarily preclinical (see Key references)

The gene encoding the OipA protein is present in all H
Orabone AW, Do V, Cohen E
