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analyzed the effects of Isatuximab, the second anti-CD38 reagent approved by the FDA, on NK cells, which express CD16, a low affinity FcR ( Overall, these results suggest that some of the therapeutic actions of the antibody are mediated by direct signaling through the CD38 molecule, without the effects driven by FcRs, at least in the NK cells tested in vitro

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PRODUODOPA was launched in the European Union in January 2024, backed by extensive clinical research, including three significant studies that demonstrated its efficacy, safety, and tolerability

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