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Lianli L, Mao J, Wang X et al

This B12-intrinsic factor complex travels to the ileum (the last section of the small intestine), where it is absorbed into the bloodstream

To investigate, Huiying Li, a molecular pharmacologist at the University of California-Los Angeles, and her team decided to focus on high levels of B12 as a possible culprit, based on research from the past six decades thats linked it to higher instances of the condition

Side effects from B12 supplementation are uncommon but may include: Mild gastrointestinal symptoms such as nausea or diarrhoea, typically with very high oral doses Headache or dizziness in some individuals Skin reactions (rash, itching) at injection sites when using intramuscular preparations Rare but serious allergic reactions, including anaphylaxis with injectable forms Hypokalaemia (low potassium) may occur during rapid correction of severe megaloblastic anaemia If you experience symptoms of a severe allergic reaction (difficulty breathing, severe rash, swelling of face or throat) after taking B12, seek immediate medical attention

A relatively long-term solution for skin lightening is laser treatment