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Many people report that food no longer drives their thoughts or behavior in the same way. In 2012, Skibickas lab was the first to demonstrate reduced alcohol reward and motivation in animal models treated with a GLP-1 analog

10.1093/bioinformatics/btw514 85 YanY.WenZ.WangX.HuangS

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However, individual inflammatory reduction varies based on baseline metabolic health, genetic factors, and adiposity patterns rather than dose alone

The primary endpoint was the percent change in body weight over the 72 weeks, and the key secondary endpoints were a weight reduction of at least 10%, 15%, 20%, and 25% and a change in waist circumference