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Description
Tirzepatide is an acylated peptide engineered to activate the GIP and GLP-1 receptors, key mediators of insulin secretion that are also expressed in regions of the brain that regulate food intake

Tirzepatide could be a starting point for GLP-1 playbook

doi: 10.3389/fmicb.2017.01804 133 WuH.RebelloO.CrostE

Time-restricted feeding improves blood glucose and insulin sensitivity in overweight patients with type 2 diabetes: a randomised controlled trial

But it suggests that semaglutide, combined with weight loss and improved insulin sensitivity, can significantly reduce insulin requirements for many people
