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In fact, the majority of patients showed stable weight or continued weight loss after their last documented GLP-1RA prescription in the participating health systems.Notably, LLM-enabled curation of clinical notes revealed that patients without weight regain were significantly more likely to have documented exercise counseling after their last prescription, suggesting that continued physical activity may play a role in sustaining weight loss after GLP-1RA discontinuation

GLP-1: Increase in GLUT4 expression by activating AMPK

This medication, initially developed for managing Obesity and type 2 diabetes, has proven to be highly effective in promoting significant weight loss