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The good news is that regulators are taking actions to address these problems

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Funding: Supported by NIH grants P30 DK056341 (Washington University Nutrition and Obesity Research Center), P30 DK020579 (Washington University Diabetes Research Center), UL1 TR000448 (Washington University Institute of Clinical and Translational Sciences), and T32 DK007120, and the Barnes-Jewish Hospital Foundation

As of 2024, some plans may cover semaglutide 2.4 mg (Wegovy) for cardiovascular risk reduction in eligible patients, but Medicare does not cover medications prescribed solely for weight loss due to statutory exclusions

In both diabetic and non-diabetic patients presenting class II/IV heart failure, GLP-1 infusion led to an improvement of left ventricular (LV) ejection fraction, myocardial ventilation oxygen consumption, 6-min walk distance, and quality of life [50]