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For urgent but non-emergency medical concerns, contact your local urgent care or emergency room

Similarly, patients who underwent esophagectomy for cancer present elevated postprandial levels of GLP-1 relative to healthy control subjects and also present an increase in computer mouse clicks for chocolate following sc injection of octreotide, whereas healthy controls do not [100]

Researchers who have studied it understand the core mechanism: GLP-1 receptor (GLP-1R) agonism produces glucose-dependent insulin secretion from pancreatic beta cells, suppresses glucagon release from alpha cells, slows gastric emptying, and engages hypothalamic appetite circuits specifically the arcuate nucleus to reduce caloric intake through neuropeptide Y/AgRP suppression and POMC/CART activation

Box, MD, can be contacted at [email protected].