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Some of the symptoms include dehydration, cramping, diarrhea, fatigue, difficulty focusing and more severe risks including pancreatitis and thyroid cancer

The supply update likely spells the end of widespread GLP-1 compounding in the U.S., which became an immensely popular avenue for patients to access weight loss drugs while Novo and Lillys branded products were in shortage

Unlike semaglutide, where plateaus are common around month 4 to 6, tirzepatide users in clinical trials showed more sustained weight loss curves, likely because the dual mechanism provides a broader metabolic stimulus that is harder for the body to fully adapt to

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That changed in 2022 when 0.1 percent of patients had a prescription, coinciding with Mounjaros approval by the FDA in 2022
