semaglutide diet guidelines Plan: Best Foods to Eat & Avoid semaglutide dietary recommendations meals protein

Your provider can adjust dosing or discuss alternative options based on your response

Inhibiting DPP-4 enzyme activity The enzyme dipeptidyl peptidase-4 (DPP-4) rapidly breaks down natural GLP-1, giving it a half-life of only 1-2 minutes

Osmotic types like polyethylene glycol and stool softeners are preferred because they work gently without forcing bowel movements

It mimics two natural hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

Results While GLP-1 and GIP agonists demonstrate significant metabolic benefits, their long-term use is often limited by gastrointestinal side effects and psychological impacts