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7.0% to 10.5% [53 to 91 mmol/mol] for SUSTAIN 2 and 3) were randomized to semaglutide 0.5 mg, semaglutide 1.0 mg or a comparator: placebo (SUSTAIN 1, 5), sitagliptin 100 mg (SUSTAIN 2), exenatide ER (SUSTAIN 3), and titrated insulin glargine (SUSTAIN 4) for 30 or 56 weeks.15, 16, 17, 18, 19 Subjects were followed throughout the planned trial period

The reabsorption of ketones in proximal tubules occurs via sodium-dependent monocarboxylate transporters (SMCT1 and SMCT2) which is dependent on sodium gradient (lumen to proximal tubule)

Ask for baseline labs (A1c, lipids, liver panel) and regular follow-up visits

Statute of limitations deadlines vary across jurisdictions: Two-year limitations: California, Texas, Pennsylvania, New Jersey, Illinois, Florida Three-year limitations: New York, North Carolina, South Carolina, Maryland Variable periods: Delaware (2-3 years depending on discoverability) Special rules: Some states have different deadlines for wrongful death claims The discovery rule, recognized in most jurisdictions, delays the start of the limitations period until the plaintiff knew or reasonably should have known about both the injury and its potential connection to Ozempic use

Avoid repeated freezing and thawing, which can reduce potency