is oral glp 1 effective FDA Approves Semaglutide as the First Oral GLP-1 Pill The Great (Oral) GLP-1 Scare

"The GLP-1 shortage challenges are exacerbated by a lack of accurate, up-to-date, and accessible GLP-1 supply information

Specifically, dulaglutide, liraglutide, and injectable semaglutide are associated with reduced cardiovascular risk (Trujillo, 2021)

Additionally, GLP-1 RAs with established CV benefitsspecifically liraglutide, subcutaneous semaglutide, dulaglutide, and efpeglenatideare recommended for patients with T2DM and ASCVD to reduce CV events, regardless of baseline or target HbA1c levels or concurrent glucose-lowering therapy (Class I, LoE A)

None produce the dramatic results of semaglutide or tirzepatide, but several are considered safe during lactation and can produce meaningful weight loss

Consequently, choosing anti-hyperglycemic therapies with proven cardiovascular and renal benefits is now a cornerstone of T2DM management [2]