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52 The homology of both ligands, IGFs, and insulin is estimated to be at 50% which partially contributes to the cross-activation of IGF-1R and IR
However, factors like stress, poor diet, and UV exposure reduce glutathione levels leading to dull, uneven skin
discovered a new compound, erastin, which had a selectively lethal effect on RAS-expressing cancer cells, but the manner of cell death was different from what had been seen before
Acta 190 , 371 (2023)
